Background Killed whole-cell oral cholera vaccines (kOCVs) are becoming a standard
cholera control and prevention tool. However, vaccine efficacy and direct effectiveness …

There is a critical need for improved diagnosis of tuberculosis in children, particularly in
young children with intrathoracic disease as this represents the most common type of …

Children younger than 18 years account for a substantial proportion of patients with
tuberculosis worldwide. Available treatments for paediatric drug-susceptible and drug …

Background Pneumonia, the leading infectious cause of child mortality globally, mainly
afflicts developing countries. This prospective observational study aimed to assess the …

Background The safety, efficacy, and appropriate timing of isoniazid therapy to prevent
tuberculosis in pregnant women with human immunodeficiency virus (HIV) infection who are …

Background Globally, the population of adolescents living with perinatally acquired HIV
(APHs) continues to expand. In this study, we pooled data from observational pediatric HIV …

More than 1 million HIV-exposed, uninfected infants are born annually to HIV-positive
mothers worldwide. This growing population of infants experiences twice the mortality of HIV …

Although 23 antiretroviral drugs are approved for use in adults, only six are approved by
regulatory authorities for use in term neonates born to women with HIV, with even fewer …

We report investigation of 22 TB cases with positive Xpert MTB/RIF result for resistance to
Rifampin and “Very Low” MTB detection level. Twelve cases were false positive without rpoB …

Successful and sustained efforts have been made to curtail the major cholera epidemic that
occurred in Haiti in 2010 with the promotion of hygiene and sanitation measures, training of …