Tuberculosis in pregnant and postpartum women: epidemiology, management, and research gaps

JS Mathad, A Gupta - Clinical infectious diseases, 2012 - academic.oup.com
Tuberculosis is most common during a woman's reproductive years and is a major cause of
maternal–child mortality. National guidelines for screening and management vary widely …

Screening and diagnosis of gestational diabetes in India: a systematic review and meta-analysis

KT Li, S Naik, M Alexander, JS Mathad - Acta diabetologica, 2018 - Springer
Aims Although diabetes is rapidly increasing in India, there is no national consensus on best
practices for screening, diagnosis, and management of gestational diabetes mellitus (GDM) …

Pulmonary infections in pregnancy

JS Mathad, A Gupta - … in Respiratory and Critical Care Medicine, 2017 - thieme-connect.com
Pregnant women experience physiological and immunological changes that increase the
risk or severity of certain pulmonary infections. These changes also affect drug disposition …

Sex-related differences in inflammatory and immune activation markers before and after combined antiretroviral therapy initiation

JS Mathad, N Gupte, A Balagopal… - JAIDS Journal of …, 2016 - journals.lww.com
Background: Women progress to death at the same rate as men despite lower plasma HIV
RNA (viral load). We investigated sex-specific differences in immune activation and …

[HTML][HTML] Pregnancy differentially impacts performance of latent tuberculosis diagnostics in a high-burden setting

JS Mathad, R Bhosale, V Sangar, V Mave, N Gupte… - PloS one, 2014 - journals.plos.org
Background Targeted screening for latent TB infection (LTBI) in vulnerable populations is a
recommended TB control strategy. Pregnant women are at high risk for developing TB and …

[HTML][HTML] Clinically relevant antibiotic resistance genes are linked to a limited set of taxa within gut microbiome worldwide

PJ Diebold, MW Rhee, Q Shi, NV Trung… - Nature …, 2023 - nature.com
The acquisition of antimicrobial resistance (AR) genes has rendered important pathogens
nearly or fully unresponsive to antibiotics. It has been suggested that pathogens acquire AR …

Association of maternal inflammation during pregnancy with birth outcomes and infant growth among women with or without HIV in India

M Shafiq, JS Mathad, S Naik, M Alexander… - JAMA Network …, 2021 - jamanetwork.com
Importance The association of elevated levels of specific inflammatory markers during
pregnancy with adverse birth outcomes and infant growth could indicate pathways for …

Toward earlier inclusion of pregnant and postpartum women in tuberculosis drug trials: consensus statements from an international expert panel

A Gupta, JS Mathad, SM Abdel-Rahman… - Clinical Infectious …, 2016 - academic.oup.com
Tuberculosis is a major cause of morbidity and mortality in women of childbearing age (15–
44 years). Despite increased tuberculosis risk during pregnancy, optimal clinical treatment …

Quantitative IFN-γ and IL-2 response associated with latent tuberculosis test discordance in HIV-infected pregnant women

JS Mathad, R Bhosale, U Balasubramanian… - American journal of …, 2016 - atsjournals.org
Rationale: Pregnant women with latent tuberculosis infection (LTBI) are at high risk for
development of TB, especially if infected with HIV. Objectives: To assess the performance of …

Pharmacokinetics and safety of 3 months of weekly rifapentine and isoniazid for tuberculosis prevention in pregnant women

JS Mathad, R Savic, P Britto… - Clinical Infectious …, 2022 - academic.oup.com
Background Pregnancy increases the risk of tuberculosis and its complications. A 3-month
regimen of weekly isoniazid and rifapentine (3HP) is safe and effective for tuberculosis …