[HTML][HTML] Artificial exosomes for translational nanomedicine

YJ Li, JY Wu, J Liu, W Xu, X Qiu, S Huang… - Journal of …, 2021 - Springer
Exosomes are lipid bilayer membrane vesicles and are emerging as competent
nanocarriers for drug delivery. The clinical translation of exosomes faces many challenges …

Apoptotic bodies for advanced drug delivery and therapy

M Zhou, YJ Li, YC Tang, XY Hao, WJ Xu… - Journal of Controlled …, 2022 - Elsevier
Extracellular vesicles (EVs) have emerged as promising candidates for multiple biomedical
applications. Major types of EVs include exosomes, microvesicles, and apoptotic bodies …

[HTML][HTML] Anticancer Activity and Mechanism of Xanthohumol: A Prenylated Flavonoid From Hops (Humulus lupulus L.)

CH Jiang, TL Sun, DX Xiang, SS Wei… - Frontiers in …, 2018 - frontiersin.org
It has been observed that many phytochemicals, frequently present in foods or beverages,
show potent chemopreventive or therapeutic properties that selectively affect cancer cells …

Gemcitabine loaded autologous exosomes for effective and safe chemotherapy of pancreatic cancer

YJ Li, JY Wu, JM Wang, XB Hu, JX Cai, DX Xiang - Acta biomaterialia, 2020 - Elsevier
Pancreatic cancer remains one of the most highly lethal diseases with very poor prognosis.
Gemcitabine (GEM) is the first-line chemotherapeutic drug for pancreatic cancer treatment …

Preservation of small extracellular vesicles for functional analysis and therapeutic applications: a comparative evaluation of storage conditions

JY Wu, YJ Li, XB Hu, S Huang, DX Xiang - Drug Delivery, 2021 - Taylor & Francis
Extracellular vesicles (EVs) are nanovesicles involved in multiple biological functions. Small
EVs (sEVs) are emerging as therapeutics and drug delivery systems for their contents …

Exosomes and biomimetic nanovesicles-mediated anti-glioblastoma therapy: a head-to-head comparison

JY Wu, YJ Li, XB Hu, S Huang, S Luo, T Tang… - Journal of Controlled …, 2021 - Elsevier
Exosomes (Exos) are promising vehicles for brain drug delivery due to nanosize and the
ability to breach the blood–brain barrier (BBB). But the low yield of natural exosomes limits …

[HTML][HTML] Bacterial outer membrane vesicles-based therapeutic platform eradicates triple-negative breast tumor by combinational photodynamic/chemo …

Y Li, J Wu, X Qiu, S Dong, J He, J Liu, W Xu, S Huang… - Bioactive Materials, 2023 - Elsevier
Bacterial outer membrane vesicles (OMVs) are potent immuno-stimulating agents and have
the potentials to be bioengineered as platforms for antitumor nanomedicine. In this study …

[HTML][HTML] Multifunctional exosome-mimetics for targeted anti-glioblastoma therapy by manipulating protein corona

JY Wu, YJ Li, J Wang, XB Hu, S Huang, S Luo… - Journal of …, 2021 - Springer
Targeted drug delivery to the glioblastoma (GBM) overcoming blood–brain barrier (BBB) has
been challenging. Exosomes are promising vehicles for brain tumor drug delivery, but the …

Emerging strategies for labeling and tracking of extracellular vesicles

YJ Li, JY Wu, JM Wang, XB Hu, DX Xiang - Journal of controlled release, 2020 - Elsevier
Extracellular vesicles (EVs) are cell-derived lipid bilayer-enclosed nanovesicles. EVs are
emerging as keys for identifying molecular mechanisms by mediating intercellular …

[HTML][HTML] Nonviral delivery systems for antisense oligonucleotide therapeutics

S Huang, XY Hao, YJ Li, JY Wu, DX Xiang, S Luo - Biomaterials Research, 2022 - Springer
Antisense oligonucleotides (ASOs) are an important tool for the treatment of many genetic
disorders. However, similar to other gene drugs, vectors are often required to protect them …