Table 3

Pentavalent vaccine uptake rate before and after immunisation service integration (accounting for seasonality bias)

Pentavalent vaccine uptake rate before (July–December 2018) and after (July–December 2019) immunisation service integration
Rumbek Centre countyBefore, %After, %Immunisation coverage rate ratio (mean and 95% CI)P value
First dose78.1995.561.22 (1.08 to 2.56)<0.001*
Second dose66.2769.411.05 (0.50 to 2.20)0.102
Third dose46.2961.831.34 (1.04 to 2.80)<0.001*
Drop-out rate54.4140.000.74 (0.32 to 0.90)<0.001*
Rumbek East countyBefore, %After, %Immunisation coverage rate ratio (mean and 95% CI)P value
First dose63.4177.411.22 (1.05 to 2.56)<0.001*
Second dose55.0762.101.13 (0.54 to 2.37)0.314
Third dose49.2462.561.27 (1.06 to 2.67)<0.001*
Drop-out rate33.4928.300.85 (0.40 to 0.97)<0.001*
  • To address seasonally induced effectiveness bias, the intervention impact during the postintervention period (July–December) in 2019 was compared with the same preintervention period (July–December) in 2018. Pentavalent vaccine uptake for the three doses and drop-out rates before (July–December 2018) and after (July–December 2019) immunisation service integration into the nutrition programmes and paediatric outpatient departments of primary healthcare centres of Rumbek Centre and Rumbek East counties, respectively.

  • Standard normal distribution test (Z-test) was used to generate 95% CIs for immunisation coverage rate ratio.

  • *Immunisation coverage rate ratio is significant.