Table 2

10-year mortality probabilities for non-statin prescription, and the absolute risk reduction (ARR) and relative risk reduction (RRR) in all-cause mortality associated with current statin prescription by risk profiles, presented in percentages

MenNo statinsStatinsStatins
Age QRISK2DeathsBorn 1930–35
ARR/RRR
Born 1936–40
ARR/RRR
Profile A
65<207%0.86/12.621.60/23.36
20–408%0.96/12.571.77/23.28
≥40 or CVD10%1.24/12.432.29/23.06
70<2013%1.62/12.733.46/27.14
20–4014%1.79/12.633.83/26.98
≥40 or CVD20%2.40/12.275.14/26.34
75<20NANANA
20–4025%4.96/19.567.25/28.58
≥40 or CVD34%6.34/18.569.32/27.29
80<20NANANA
20–4024%5.74/23.958.21/34.27
≥40 or CVD30%7.01/23.1510.08/33.28
Profile B
65<2037%3.93/10.537.44/19.93
20–4041%4.17/10.267.91/19.48
≥40 or CVD50%4.71/9.469.03/18.13
70<2049%4.86/9.9110.80/22.04
20–4053%5.05/9.5211.30/21.30
≥40 or CVD66%5.33/8.1112.24/18.62
75<20NANANA
20–4069%9.11/13.2013.93/20.18
≥40 or CVD81%8.35/10.2813.12/16.15
80<20NANANA
20–4060%11.04/18.2916.41/27.18
≥40 or CVD70%11.30/16.0417.09/24.26
Women No statins Statins Statins
Age QRISK2DeathsBorn 1930–35
ARR/RRR
Born 1936–40
ARR/RRR
Profile A
65<205%0.67/12.711.23/12.37
20–406%0.74/12.681.37/12.34
≥40 or CVD8%0.96/12.571.78/12.25
70<2010%1.29/12.902.74/16.71
20–4011%1.43/12.833.04/16.63
≥40 or CVD15%1.93/12.554.14/16.33
75<2020%4.03/20.125.86/11.49
20–4020%4.07/20.105.93/11.48
≥40 or CVD28%5.33/19.317.80/11.09
80<20NANANA
20–4019%4.69/24.526.69/13.84
≥40 or CVD24%5.83/23.898.35/13.54
Profile B
65<2030%3.32/11.096.24/10.99
20–4033%3.56/10.886.71/10.81
≥40 or CVD41%4.18/10.257.94/10.26
70<2040%4.32/10.679.50/14.30
20–4044%4.57/10.3610.10/13.95
≥40 or CVD56%5.17/9.1911.63/12.66
75<2059%8.89/15.0413.40/8.97
20–4060%8.91/14.9613.44/8.93
≥40 or CVD73%9.03/12.4413.90/7.66
80<20NANANA
20–4051%10.25/20.0015.04/11.69
≥40 or CVD61%11.09/18.1316.50/10.80
  • Profile A: healthiest and wealthiest profile included non-smokers without a diagnosis of diabetes, hypertension, hypercholesterolemia, or chronic kidney disease, and resident in the least deprived area.Profile B: least healthy and wealthy profile included smokers with a diagnosis of diabetes, untreated hypertension, and resident in the most deprived area.

  • CVD, cardiovascular disease; NA, not available.