Table 1

Demographic characteristics and usage patterns of any psychoactive prescription medications among US youth aged 12–17 years, National Survey of Drug Use and Health, 2015–2018

Past-year use of any psychoactive prescription medications*Past-year misuse† (among any users)Past-year substance use disorder‡ (among any users)Past-year use of 2 or more psychoactive prescription medications
N (%)Prevalence (%)Proportion (%)Proportion (%)Prevalence (%)
Overall54 866 (100)25.0 (24.5–25.4)20.9 (20.0–21.7)3.4 (3.0–3.8)5.7 (5.5–6.0)
Sex
 Female26 834 (49.1)25.2 (24.5–25.9)22.1 (20.9–23.4)4.2 (3.6–4.8)6.2 (5.8–6.5)
 Male28 032 (50.9)24.7 (24.1–25.4)19.6 (18.4–20.8)2.6 (2.1–3.0)5.3 (5.0–5.6)
 Age, years
 12–1317 517 (31.3)17.9 (17.2–18.6)10.8 (9.4–12.1)1.8 (1.2–2.3)2.8 (2.5–3.1)
 14–1518 762 (34.4)24.4 (23.6–25.2)19.1 (17.7–20.6)3.6 (2.9–4.3)5.4 (5.0–5.8)
 16–1718 587 (34.3)31.9 (31.1–32.8)27.3 (25.8–28.8)4.0 (3.4–4.6)8.7 (8.2–9.2)
Race/ethnicity
 White (non-Hispanic)29 109 (52.9)26.7 (26.0–27.3)19.9 (18.8–21.0)3.1 (2.7–3.6)6.6 (6.2–6.9)
 Black (non-Hispanic)7236 (13.7)23.9 (22.7–25.1)19.1 (16.9–21.3)2.5 (1.7–3.4)4.3 (3.7–4.9)
 Asian (non-Hispanic)2151 (5.4)17.9 (15.8–20.0)19.8 (14.6–24.9)3.3 (1.2–5.5)3.4 (2.4–4.4)
 Hispanic12 194 (23.7)23.1 (22.0–24.1)24.0 (21.8–26.2)4.3 (3.3–5.4)4.9 (4.4–5.4)
 Other (non-Hispanic)4176 (4.3)26.6 (24.7–28.5)23.4 (19.9–26.8)4.1 (2.7–5.5)7.3 (6.2–8.3)
Education
 Middle school or less10 910 (19.5)16.7 (15.8–17.6)10.4 (8.6–12.2)1.7 (0.9–2.5)2.7 (2.3–3.0)
 <High school28 260 (51.5)24.0 (23.4–24.7)18.2 (17.0–19.4)3.3 (2.7–3.8)5.2 (4.9–5.5)
 High school9046 (16.5)30.7 (29.5–32.0)26.5 (24.4–28.6)4.7 (3.7–5.7)7.9 (7.2–8.6)
 Some college6577 (12.4)33.8 (32.3–35.3)29.8 (27.4–32.3)3.5 (2.6–4.4)9.7 (8.8–10.6)
 College+73 (0.2)50.4 (36.4–64.5)27.9 (11.0–44.8)12.7 (4.2–21.3)
Poverty level§
 Poverty11 917 (22)23.7 (22.7–24.7)22.7 (20.7–24.7)4.4 (3.5–5.4)5.6 (5.0–6.1)
 up to 2 × threshold12 377 (22)24.8 (23.8–25.8)21.9 (20.0–23.8)3.5 (2.7–4.3)5.9 (5.4–6.4)
 >2 x threshold30 572 (56.1)25.5 (24.9–26.1)19.8 (18.7–20.9)2.9 (2.5–3.4)5.7 (5.4–6.1)
Health insurance
 No insurance2010 (4.5)21.8 (19.5–24.2)30.0 (24.5–35.4)3.6 (1.4–5.7)5.2 (4.1–6.4)
 Private31 187 (57.5)25.1 (24.5–25.7)19.8 (18.7–21.0)3.0 (2.5–3.5)5.6 (5.3–5.9)
 Medicaid19 525 (34.4)24.9 (24.1–25.7)21.6 (20.1–23.1)3.9 (3.2–4.7)5.9 (5.5–6.3)
 Medicare only54 (0.1)
 Other (non-Hispanic)2090 (3.5)26.9 (24.2–29.5)19.6 (15.1–24.1)3.5 (1.6–5.4)6.8 (5.2–8.4)
Metro status¶
 Metro43 850 (86.1)24.8 (24.3–25.3)21.1 (20.1–22.1)3.4 (2.9–3.8)5.7 (5.4–6.0)
 Non-metro11 016 (13.9)25.9 (24.7–27.0)19.5 (17.5–21.5)3.4 (2.5–4.4)5.9 (5.3–6.5)
Recency of non-prescription substance** use
 Never used any substance34 698 (64)17.4 (16.9–17.9)6.8 (5.9–7.6)0.4 (0.2–0.6)2.5 (2.3–2.7)
 Used within past 30 days8063 (14.2)46.7 (45.3–48.2)45.3 (43.2–47.3)8.4 (7.3–9.6)18.5 (17.4–19.7)
 Used during past 31 days to 12months7352 (13.3)33.3 (31.9–34.7)22.0 (19.9–24.2)3.5 (2.5–4.5)7.0 (6.3–7.7)
 Used more than 12 months ago4753 (8.5)32.5 (30.8–34.3)17.2 (14.7–19.8)3.0 (1.9–4.1)7.0 (6.0–7.9)
Number of non-prescription substances used (past 30 days)
 046 803 (85.8)21.4 (20.9–21.8)12.0 (11.2–12.9)1.6 (1.2–1.9)3.6 (3.4–3.8)
 14721 (8.5)39.3 (37.5–41.1)30.9 (28.2–33.7)5.0 (3.7–6.2)11.6 (10.4–12.8)
 22011 (3.4)51.6 (48.7–54.5)51.6 (47.6–55.7)7.8 (5.7–9.8)21.4 (19.0–23.8)
 3929 (1.6)63.4 (59.4–67.5)64.6 (59.7–69.5)12 (8.7–15.3)34.0 (30.1–37.9)
 4316 (0.5)74.7 (67.8–81.5)77.2 (69.9–84.6)21.7 (14.2–29.3)50.0 (42.5–57.6)
 5+86 (0.1)92.9 (85.8–100.0)88.6 (76.1–100.0)41.4 (26.4–56.5)84.2 (74.8–93.6)
Number of non-prescription substances used (past year)
 039 451 (72.5)19.2 (18.7–19.7)8.9 (8.0–9.7)0.9 (0.7–1.2)3.0 (2.8–3.2)
 17884 (14.4)31.7 (30.3–33.0)17.7 (15.7–19.6)2.3 (1.5–3.0)6.4 (5.7–7.1)
 23852 (6.8)41.3 (39.2–43.4)34.4 (31.3–37.5)5.1 (3.6–6.6)11.6 (10.3–12.9)
 32016 (3.5)49.8 (46.9–52.6)48.6 (44.6–52.6)8.0 (5.9–10.1)18.7 (16.5–20.9)
 41101 (1.9)62.8 (59.0–66.7)60.8 (56.0–65.6)11.5 (8.5–14.6)33.3 (29.6–37.0)
 5+562 (0.9)84.8 (81.2–88.4)83.5 (78.6–88.5)24.8 (19.4–30.2)63.4 (58.2–68.6)
  • Psychoactive prescription medications assessed in NSDUH include opioids, stimulants, tranquillisers and sedatives. Estimates in bold type indicate statistically significant differences within the demographic subgroup. Estimates with relative standard errors ≥40% were suppressed (−).

  • *Any use was use of any of the four psychoactive prescription medications assessed.

  • †Misuse was defined as a report by the respondent that they had used the psychoactive prescription medication in the past year in any way not directed or prescribed, including use without a prescription of individual’s own, or deviations in the dose (greater amounts), frequency (more often) or duration (longer).

  • ‡Substance use disorder was defined as having indications of dependence or abuse using the DSM-IV definition.

  • §Poverty status was defined using the Federal Poverty Threshold of each survey year.

  • ¶Metro status assessed whether the respondent lived in a metropolitan statistical area or not delineated by the Office of Management and Budget.

  • **Non-prescription substances include alcohol, cigarettes, cigars, marijuana, cocaine, heroin, inhalants and hallucinogens.