Table 3

Demographic characteristics and usage patterns of any psychoactive prescription medications among US young adults aged 18–25 years, National Survey of Drug Use and Health, 2015–2018

Past-year use of any psychoactive prescription medications*Past-year misuse †(among any usersPast-year substance use disorder ‡ (among any users)Past-year use of 2 or more psychoactive prescription medications
N (%)Prevalence (%)Proportion (%)Proportion (%)Prevalence (%)
Overall55 690 (100)41.0 (40.4–41.5)34.7 (33.9–35.5)4.2 (3.9–4.5)13.4 (13.0–13.8)
Sex
 Female28 994 (49.8)44.4 (43.7–45.1)30.4 (29.4–31.4)3.5 (3.1–3.9)14.2 (13.7–14.7)
 Male26 696 (50.2)37.6 (36.8–38.3)39.6 (38.4–40.9)5.0 (4.5–5.6)12.6 (12.1–13.1)
Age, years
 18–2020 335 (37.4)38.2 (37.3–39.0)34.7 (33.4–36.1)4.5 (4.0–5.1)12.1 (11.6–12.7)
 21–2535 355 (62.6)42.6 (42.0–43.3)34.6 (33.6–35.6)4.0 (3.6–4.4)14.2 (13.7–14.6)
Race/ethnicity
 White (non-Hispanic)29 846 (54.3)46.2 (45.5–46.9)37.3 (36.3–38.3)4.7 (4.2–5.1)17.1 (16.6–17.7)
 Black (non-Hispanic)7812 (14.1)36.1 (34.9–37.4)26.0 (24.1–28.0)3.0 (2.2–3.8)8.1 (7.4–8.9)
 Asian (non-Hispanic)2741 (6.2)23.7 (21.7–25.7)29.2 (24.8–33.7)2.7 (1.2–4.2)5.4 (4.3–6.4)
 Hispanic11 667 (21.9)35.4 (34.2–36.6)32.5 (30.5–34.4)3.6 (2.9–4.4)9.6 (8.9–10.3)
 Other (non-Hispanic)3624 (3.5)45.6 (43.2–48.0)36.8 (33.2–40.3)5.3 (3.6–6.9)15.1 (13.4–16.9)
Education
 Middle school or less11 471 (21.7)41.0 (39.9–42.2)35.4 (33.7–37.2)2.7 (2.1–3.3)13.2 (12.4–14.0)
 <High school1043 (1.6)37.0 (33.3–40.7)34.8 (28.7–40.8)7.1 (4.1–10.1)13.9 (11.2–16.6)
 High school1196 (2)43.7 (40.0–47.3)33.9 (28.8–39.1)6.1 (3.6–8.6)14.6 (12.1–17.2)
 Some college23 660 (40.5)38.0 (37.2–38.8)32.0 (30.8–33.3)4.8 (4.3–5.4)11.6 (11.1–12.2)
 College+18 320 (34.2)44.5 (43.5–45.4)36.9 (35.5–38.3)4.2 (3.7–4.8)15.5 (14.8–16.2)
Poverty level §
 Poverty14 841 (26.2)40.7 (39.7–41.8)34.7 (33.1–36.2)4.0 (3.4–4.6)13.0 (12.3–13.7)
 up to 2 x threshold13 617 (24.2)39.8 (38.8–40.9)32.4 (30.8–34.0)4.2 (3.5–4.8)12.3 (11.6–12.9)
 >2 x threshold25 569 (49.6)41.7 (40.9–42.4)35.6 (34.4–36.8)4.4 (3.9–4.9)14.3 (13.7–14.8)
Health insurance
 No insurance7589 (14.3)35.8 (34.4–37.2)36.2 (33.9–38.5)4.8 (3.8–5.8)11.4 (10.5–12.3)
 Private32 454 (59.7)42.5 (41.8–43.2)36.4 (35.4–37.4)4.0 (3.6–4.5)14.5 (14.0–15.0)
 Medicaid11 557 (19.2)40.7 (39.5–41.9)29.0 (27.3–30.7)4.7 (4.0–5.5)12.2 (11.4–13.0)
 Medicare only137 (0.2)47.3 (37.2–57.4)39.3 (24.5–54.0)14.2 (7.5–20.9)
 Other (non-Hispanic)3953 (6.5)39.0 (37.0–41.0)31.3 (28.3–34.4)3.1 (2.1–4.1)11.0 (9.8–12.3)
Metro status¶
 Metro45 231 (87.3)40.7 (40.1–41.3)35.0 (34.2–35.9)4.2 (3.8–4.5)13.4 (13.0–13.8)
 Non-metro10 459 (12.7)42.9 (41.6–44.1)32.3 (30.4–34.1)4.4 (3.6–5.2)13.7 (12.8–14.6)
Serious psychological distress**
 No42 949 (77.4)36.8 (36.2–37.4)31.5 (30.6–32.5)2.4 (2.1–2.7)10.4 (10.0–10.8)
 Yes12 741 (22.6)55.2 (54.1–56.3)41.8 (40.3–43.3)8.3 (7.5–9.1)23.7 (22.7–24.6)
Recency of non-prescription substance†† use
 Never used any substance7816 (14.5)21.1 (19.9–22.2)7.5 (6.0–9.0)0.5 (0.1–0.9)3.2 (2.8–3.7)
 Used within past 30 days36 494 (65.4)48.0 (47.3–48.6)41.4 (40.5–42.4)5.0 (4.6–5.4)17.7 (17.2–18.2)
 Used during past 31 days to 12 months7768 (13.9)33.3 (31.9–34.6)16.3 (14.5–18.0)2.2 (1.5–2.9)6.9 (6.2–7.6)
 Used more than 12 months ago3612 (6.2)31.1 (29.2–33.1)11.6 (9.3–13.9)1.6 (0.7–2.4)6.2 (5.1–7.3)
Number of non-prescription substances†† used (past 30 days)
 019 195 (34.6)27.8 (27.0–28.6)12.5 (11.4–13.6)1.5 (1.1–1.9)5.2 (4.8–5.6)
 119 270 (34.6)38.7 (37.8–39.6)25.0 (23.7–26.2)2.2 (1.8–2.6)9.9 (9.3–10.4)
 210 178 (18.1)51.9 (50.7–53.2)43.7 (42.0–45.5)4.3 (3.6–5.0)19.5 (18.5–20.4)
 34981 (9)63.3 (61.5–65.0)58.2 (56.0–60.4)7.7 (6.5–8.8)31.8 (30.1–33.5)
 41636 (3)75.0 (72.3–77.7)73.9 (70.7–77.0)12.0 (9.8–14.2)44.3 (41.2–47.4)
 5+430 (0.8)87.3 (83.5–91.2)88.0 (83.6–92.5)26.3 (20.2–32.4)63.3 (57.4–69.1)
Number of non-prescription substances†† used (past year)
 011 427 (20.7)24.1 (23.1–25.1)9.1 (7.8–10.4)0.9 (0.5–1.3)4.1 (3.7–4.6)
 117 705 (31.7)33.3 (32.4–34.2)14.7 (13.5–15.8)1.3 (1.0–1.7)6.4 (6.0–6.8)
 211 940 (21.1)43.3 (42.2–44.5)29.4 (27.8–31.0)2.4 (1.9–2.9)12.7 (11.9–13.4)
 37900 (14.1)52.5 (51.1–54.0)45.2 (43.3–47.2)4.1 (3.3–4.8)20.4 (19.3–21.6)
 44209 (7.5)64.8 (62.9–66.8)59.7 (57.4–62.1)7.4 (6.2–8.6)31.3 (29.5–33.1)
 5+2509 (4.8)82.6 (80.7–84.6)81.4 (79.3–83.6)16.6 (14.5–18.6)54.0 (51.5–56.6)
  • Psychoactive prescription medications assessed in NSDUH include opioids, stimulants, tranquillisers and sedatives. Estimates in bold type indicate statistically significant differences within the demographic subgroup. Estimates with relative standard errors ≥40% were suppressed (−).

  • *Any use was use of any of the four psychoactive prescription medications assessed.

  • †Misuse was defined as a report by the respondent that they had used the psychoactive prescription medication in the past year in any way not directed or prescribed, including use without a prescription of individual’s own, or deviations in the dose (greater amounts), frequency (more often) or duration (longer).

  • ‡Substance use disorder was defined as having indications of dependence or abuse using the DSM-IV definition.

  • §Poverty status was defined using the Federal Poverty Threshold of each survey year.

  • ¶Metro status assessed whether the respondent lived in a metropolitan statistical area or not delineated by the Office of Management and Budget.

  • **Presence of serious psychological distress was defined as Kessler-6 Psychological Distress Scale Score ≥13.

  • ††Non-prescription substances include alcohol, cigarettes, cigars, marijuana, cocaine, heroin, inhalants and hallucinogens.