Pathological characteristics of patients with COVID-19
Characteristic | No. of studies | No. of patients | Heterogeneity | Model | Meta-analysis | ||
P value | I2 (%) | R (95% CI) | P value | ||||
Leucocytosis | 21 | 3936 | <0.001 | 90.6 | Random | 0.099 (0.069 to 0.134) | <0.001 |
Normal leucocyte count | 23 | 3267 | <0.001 | 89.5 | Random | 0.647 (0.591 to 0.700) | <0.001 |
Leucopenia | 27 | 4233 | <0.001 | 89.6 | Random | 0.235 (0.194 to 0.279) | <0.001 |
Lymphopaenia | 32 | 4660 | <0.001 | 94.4 | Random | 0.476 (0.413 to 0.540) | <0.001 |
High C reactive protein | 23 | 2912 | <0.001 | 93.2 | Random | 0.659 (0.586 to 0.728) | <0.001 |
High procalcitonin | 13 | 2190 | <0.001 | 96.6 | Random | 0.167 (0.083 to 0.274) | <0.001 |
High D-dimer | 9 | 2354 | <0.001 | 90.4 | Random | 0.204 (0.147 to 0.267) | <0.001 |
High erythrocyte sedimentation rate | 7 | 455 | <0.001 | 90.4 | Random | 0.204 (0.147 to 0.267) | <0.001 |
Abnormal liver function | 11 | 2524 | <0.001 | 90.1 | Random | 0.264 (0.204 to 0.329) | <0.001 |
Abnormal renal function | 8 | 2183 | <0.001 | 96.1 | Random | 0.109 (0.045 to 0.196) | <0.001 |
High myocardial enzymes | 11 | 2541 | <0.001 | 96.1 | Random | 0.494 (0.264 to 0.725) | <0.001 |