General characteristics of the overall cohort before and after intervention
Characteristic | Preintervention (n=896) | Postintervention (n=862) | P value |
Age, years | 58±10.1 | 58.28±10.6 | 0.564 |
Male | 398 (44.4) | 382 (44.3) | 0.965 |
Current cigarette smoking | 66 (10.5) | 67 (10.3) | 0.909 |
Family history of premature CHD | 14 (1.6) | 9 (1.0) | 0.339 |
Hypertension* | 428 (47.8) | 427 (49.5) | 0.458 |
Low HDL cholesterol | 90(10) | 94 (10.9) | 0.556 |
Age: male ≥45 years or female ≥55 years | 609(68) | 591 (68.6) | 0.828 |
DM† | 193 (21.5) | 240 (27.8) | 0.002 |
ATP III risk categories: | – | – | – |
Established CHD and CHD equivalent | 301 (33.6) | 324 (37.6) | 0.08 |
2+risk factors with 10-year CHD risk‡ 10%–20% | 68 (7.6) | 87 (10.1) | 0.064 |
2+risk factors with 10-year CHD risk‡<10% | 11 (1.2) | 43 (5.0) | <0.0001 |
0–1 risk factor | 516 (57.6) | 408 (47.3) | <0.0001 |
*On antihypertensive therapy or blood pressure ≥140/90 mm Hg.
†DM diagnosis according to ADA diagnostic criteria.
‡10-year CHD risk calculated by Framingham risk score.
ADA, American Diabetes Association; ATP, Adult Treatment Panel; CHD, coronary heart disease; DM, diabete mellitus; HDL, high-density lipoprotein.