TA treatment methods and details for included studies
| Author | Year | n treated | Age range treated* | Treatment method | Treatment time | Treatment provider | Treatment setting | Follow-up visits |
| Banerjee et al9 | 2020 | 136 | 36.7±7.3 | WISAP Medical Technology GmbH, 100°C, no anaesthetic, multiple overlapping applications as needed | 40 s | Auxiliary nurse midwives† | Community clinics | 12 months |
| Campbell et al23 | 2016 | 381 | – | WISAP, 100°C–120°C, no local anaesthetic, multiple overlapping applications as needed | 30 s | Unspecified health worker | Facility | 3 months, 6 months and 12 months |
| Chigbu et al18 | 2020 | 511 | 47.1±12.6 | Device not specified, 100°C, multiple overlapping applications as needed | 45 s | Not reported | Facility | 6 months |
| Duan et al28 | 2021 | 74 | 31.5±5.2 | Liger device, 100°C, no anaesthetic, multiple overlapping applications as needed | 45 s | Gynaecologist | Facility | 4, 8 months |
| Eakin et al24 | 2018 | 5 | – | Device not specified, 100°C, no anaesthetic, multiple overlapping applications as needed | 60 s | Physician | Facility | N/A |
| Fokom Domgue et al25 | 2020 | 161 | – | WISAP Medical Technology GmbH, 100°C, multiple overlapping applications as needed | 45 s | Nurse | Primary health clinic | N/A |
| Joshi et al10 | 2013 | 124 | – | Device not specified, 105°C, no local anaesthetic, multiple overlapping applications as needed | 45 s | Unspecified health worker | Community clinics | 6 months |
| Joshi et al26 | 2015 | 27 | – | WISAP Medical Technology GmbH, 105°C, no local anaesthetic, multiple overlapping applications as needed | 45 s | Physician or Nurse† | Community clinics | N/A |
| Mungo et al19 | 2020 | 293 | 40.4±8.7 | Liger device, 100°C, no local anaesthethic, number of applications not specified | 20 s | Clinical officer—equivalent to a physician assistant in the USA† | Community clinics | 4–6 weeks |
| Naud et al22 | 2016 | 52 | 31 (27–40) | WISAP Medical Technology GmbH, 100°C, no local anaesthetic, multiple overlapping applications as needed | 20 s | Not reported | Facility | 12 months |
| Pinder et al11 | 2020 | 250 | – | Liger device, 100°C, no anaesthetic, multiple overlapping applications as needed | 40 s | Nurse | Primary health clinic | 2 weeks and 6 months |
| Sandoval et al20 | 2019 | 319 | – | Liger device, 100°C, analgesia (NSAIDs) offered post-treatment, multiple overlapping applications as needed | 45 s | Physicians† | Facility | 1 month |
| Viviano et al21 | 2017 | 110 | – | WISAP Medical Technology GmbH, 100°C, no anaesthetic, multiple applications as needed | 60 s | Gynaecologist† | Facility | 1 month |
| Zhao et al12 | 2021 | 170 | 41.0 (35–47) | WISAP Medical Technology GmbH or Liger device, 100°C–110°C, no anaesthetic, multiple applications as needed | 45 s | Physician | Primary health clinic | 1 month, 6 months, 12 months and 18 months |
| Zhao et al27 | 2020 | 96 | – | WISAP Medical Technology GmbH or Liger device, 100°C, no anaesthetic, multiple applications as needed | 45 s | Unspecified health worker | Primary health clinic | 4 weeks |
*Average ±SD or median (IQR).
†Based on personal communication with authors (Dr Partha Basu, 2021; Dr Smita Joshi, 2021; Dr Chemtai Mungo, 2021; Dr Silvia de Sanjose, 2021; and Dr Manuela Viviano, 2021).
NSAIDs, non-steroidal anti-inflamatory drugs; TA, thermal ablation.