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Clinical Tips
Antihypertensive drugs in pregnancy
  1. Rose Gasnier1,
  2. Edimárlei Gonsales Valério2 and
  3. José Geraldo Lopes Ramos3
  1. 1Post Graduate Program in Medicine, Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Brazil
  2. 2Service of Obstetrician and Gynecology, Hospital de Clínicas de Porto Alegre, Brazil
  3. 3Service of Obstetrician and Gynecology, Hospital de Clínicas de Porto Alegre, Brazil; Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
  1. Corresponding author: Rose Gasnier, Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Brazil gasnier.rose{at}gmail.com

Abstract

Chronic hypertension complicates 3%-5% of pregnancies and gestational hypertension occurs in 6% of pregnancies. Preeclampsia complicates 25% of the pregnancies with chronic hypertension, and approximately 15%-45% of the patients with gestational hypertension will develop preeclampsia, a dangerous condition that harms the maternal and fetal safety. Antihypertensive medication is used to treat severe hypertension to prevent serious maternal and fetal complications, but there is no consensus on when and how to treat mild-to-moderate hypertension in pregnancy. This article reviews the usage, effect and safety of first, second and third line antihypertensive drugs for mild-to-moderate hypertension in pregnancy.

  • Gestational hypertension
  • Mild-to-moderate hypertension
  • Antihypertensive drugs

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License (CC BY-NC 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc/4.0/.

https://doi.org/10.15212/FMCH.2013.0106

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